Vitamins, cofactors and other substrates metabolism
Cryptosporidium muris
- CoA biosynthesis
- Lipoic acid incorporation
- NADP synthesis - NAD is salvaged from host and phosphorylated to NADP
- Pyridoxal phosphate (Vitamin B6) salvage
- Recycling of folate - Thymidylate synthase cycle
- Ubiquinone metabolism
Cryptosporidium parvum
- CoA biosynthesis
- Lipoic acid incorporation - Mitochondrial lipoic acid incorporation is absent. This is because no dehydrogenase enzyme complexes are present in C. parvum mitochondria.
- NADP synthesis - NAD is salvaged from host and phosphorylated to NADP
- Pyridoxal phosphate (Vitamin B6) salvage - The enzymes involved in pyridoxal phosphate metabolism in C. muris is missing in C. parvum. The examples of PLP dependent enzymes in C. parvum genome is present in the page: Pyridoxal phosphate dependent enzymes in C. parvum genome
- Recycling of folate - Thymidylate synthase cycle
- Ubiquinone metabolism
Cryptosporidium hominis
- CoA biosynthesis
- Lipoic acid incorporation - Mitochondrial lipoic acid incorporation is absent. This is because no dehydrogenase enzyme complexes are present in C. hominis mitochondria.
- NADP synthesis - NAD is salvaged from host and phosphorylated to NADP
- Pyridoxal phosphate (Vitamin B6) salvage - The enzymes involved in pyridoxal phosphate metabolism in C. muris is missing in C. hominis. The examples of PLP dependent enzymes in C. hominis genome is present in the page: Pyridoxal phosphate dependent enzymes in C. hominis genome
- Recycling of folate - Thymidylate synthase cycle
- Ubiquinone metabolism