Missing enzymes in apicomplexan gene models

Enzyme Name EC Number


Tgo Nca Cmu Cpa Cho Bbo Tpa Ta
IMP dehydrogenase                  
Shikimate dehydrogenase                  
Homoserine dehydrogenase                  
Sphingolipid delta-4 desaturase 1.14.-.-                  
[methionine synthase] reductase                  
Butyryl-CoA dehydrogenase                  
Glycine dehydrogenase                  
Methyltransferase, MiaB 2.1.-.-                  
Homocysteine S-methyltransferase                  
Glucosamine-phosphate N-acetyltransferase

Diamine N-acetyltransferase                  
Acetyl-CoA C-acetyltransferase                  
ALG5 - Dolichyl-phosphate beta-glucosyltransferase                  
Dolichyl-diphosphooligosaccharide-protein glycotransferase

Dolichyl-phosphate-mannose- glycolipid alpha-mannosyltransferase

ALG11 - alpha-1,2-mannosyltransferase                  
ALG14 - UDP-GlcNAc:dolichyl pyrophosphoryl-GlcNAc GlcNAc transferase

ALG8 - Dol-P-Glc:Glc1-Man9-GlcNAc2-PP-Dol alpha-1,3-glucosyltransferase

ALG6 - Dol-P-Glc:Man9-GlcNAc2-PP-Dol alpha-1,3-glucosyltransferase

3-deoxy-7-phosphoheptulonate synthase                  
Adenosine kinase                  
Dephospho-CoA kinase                  
Cytidylate kinase                  
Thiamine phosphate kinase                  
Nicotinate-nucleotide adenylyltransferase                  
FAD synthetase                  
Pantetheine-phosphate adenylyltransferase                  
Acyl-ACP thiolesterase                  
Fatty-acyl-CoA thioesterase I                  
Inositol-1,4-bisphosphate 1-phosphatase                  
MAN1 - Mannosyl-oligosaccharide 1,2-alpha-mannosidase                  
N-acetylglucosaminyl phosphatidylinositol deacetylase                  
Adenosine deaminase                  
ADP-ribose diphosphatase                  
Ecto-nucleoside triphosphate diphosphohydrolase                  
ATP synthase Fo-a subunit                  
ATP synthase Fo-b subunit                  
Vacuolar ATP synthase subunit H                  
3-octaprenyl 4-hydroxybenzoate carboxy-lyase 4.1.1.-                  
Phosphopantothenoylcysteine decarboxylase                  
Dihydroneopterin aldolase                  
Aminodeoxy-chorismate lyase                  
3-dehydroquinate dehydratase                  
Methylglutaconyl-CoA hydratase                  
6-pyruvoyltetrahydropterin synthase                  
3-dehydroquinate synthase                  
Oxo-acid  lyase 4.3.1.-                  
Glyoxalase I - Lactoylglutathione lyase                  
Phosphopantothenate-cysteine ligase                  
GMP synthase                  




  The enzyme function or complete pathway is absent in the organism.



  The gene(s) for the enzyme is present in the gene models.



 The gene for the enzyme is missing in the gene models.


The full names of the abbreviations used for the organisms above are given here. Pfa - Plasmodium falciparum, Tgo - Toxoplasma gondii, Nca - Neospora caninum, Cmu - Cryptosporidium muris, Cpa - Cryptosporidium parvum, Cho - Cryptosporidium hominis, Bbo - Babesia bovis, Tpa - Theileria parva & Ta - Theileria annulata.