Missing enzymes in apicomplexan gene models

Enzyme Name EC Number

Pfa

Tgo Nca Cmu Cpa Cho Bbo Tpa Ta
IMP dehydrogenase 1.1.1.205                  
Shikimate dehydrogenase 1.1.1.25                  
Homoserine dehydrogenase 1.1.1.3                  
Sphingolipid delta-4 desaturase 1.14.-.-                  
[methionine synthase] reductase 1.16.1.8                  
Butyryl-CoA dehydrogenase 1.3.99.2                  
Glycine dehydrogenase 1.4.4.2                  
Methyltransferase, MiaB 2.1.-.-                  
Homocysteine S-methyltransferase 2.1.1.10                  
Glucosamine-phosphate N-acetyltransferase

2.3.1.4

                 
Diamine N-acetyltransferase 2.3.1.57                  
Acetyl-CoA C-acetyltransferase 2.3.1.9                  
ALG5 - Dolichyl-phosphate beta-glucosyltransferase 2.4.1.117                  
Dolichyl-diphosphooligosaccharide-protein glycotransferase

2.4.1.119

                 
Dolichyl-phosphate-mannose- glycolipid alpha-mannosyltransferase

2.4.1.130

                 
ALG11 - alpha-1,2-mannosyltransferase 2.4.1.131                  
ALG14 - UDP-GlcNAc:dolichyl pyrophosphoryl-GlcNAc GlcNAc transferase

2.4.1.141

                 
ALG8 - Dol-P-Glc:Glc1-Man9-GlcNAc2-PP-Dol alpha-1,3-glucosyltransferase

2.4.1.265

                 
ALG6 - Dol-P-Glc:Man9-GlcNAc2-PP-Dol alpha-1,3-glucosyltransferase

2.4.1.267

                 
di-trans,poly-cis-decaprenylcistransferase 2.5.1.31                  
3-deoxy-7-phosphoheptulonate synthase 2.5.1.54                  
Adenosine kinase 2.7.1.20                  
Dephospho-CoA kinase 2.7.1.24                  
Cytidylate kinase 2.7.4.14                  
Thiamine phosphate kinase 2.7.4.16                  
Nicotinate-nucleotide adenylyltransferase 2.7.7.18                  
FAD synthetase 2.7.7.2                  
Pantetheine-phosphate adenylyltransferase 2.7.7.3                  
Acyl-ACP thiolesterase 3.1.2.14                  
Fatty-acyl-CoA thioesterase I 3.1.2.2                  
Phosphatidylglycerophosphatase 3.1.3.27                  
Inositol-1,4-bisphosphate 1-phosphatase 3.1.3.57                  
MAN1 - Mannosyl-oligosaccharide 1,2-alpha-mannosidase 3.2.1.113                  
N-acetylglucosaminyl phosphatidylinositol deacetylase 3.5.1.89                  
Adenosine deaminase 3.5.4.4                  
ADP-ribose diphosphatase 3.6.1.13                  
Ecto-nucleoside triphosphate diphosphohydrolase 3.6.1.15                  
Dolichyldiphosphatase 3.6.1.43                  
Acylphosphatase 3.6.1.7                  
ATP synthase Fo-a subunit 3.6.3.14                  
ATP synthase Fo-b subunit 3.6.3.14                  
Vacuolar ATP synthase subunit H 3.6.3.14                  
3-octaprenyl 4-hydroxybenzoate carboxy-lyase 4.1.1.-                  
Phosphopantothenoylcysteine decarboxylase 4.1.1.36                  
Dihydroneopterin aldolase 4.1.2.25                  
Aminodeoxy-chorismate lyase 4.1.3.38                  
3-dehydroquinate dehydratase 4.2.1.10                  
Methylglutaconyl-CoA hydratase 4.2.1.18                  
6-pyruvoyltetrahydropterin synthase 4.2.3.12                  
3-dehydroquinate synthase 4.2.3.4                  
Oxo-acid  lyase 4.3.1.-                  
Glyoxalase I - Lactoylglutathione lyase 4.4.1.5                  
Phosphopantothenate-cysteine ligase 6.3.2.5                  
GMP synthase 6.3.5.2                  

 

 

 

  The enzyme function or complete pathway is absent in the organism.

 

 

  The gene(s) for the enzyme is present in the gene models.

 

 

 The gene for the enzyme is missing in the gene models.

 

The full names of the abbreviations used for the organisms above are given here. Pfa - Plasmodium falciparum, Tgo - Toxoplasma gondii, Nca - Neospora caninum, Cmu - Cryptosporidium muris, Cpa - Cryptosporidium parvum, Cho - Cryptosporidium hominis, Bbo - Babesia bovis, Tpa - Theileria parva & Ta - Theileria annulata.