Lipids and Glycan metabolism

Cryptosporidium muris

• Fatty acid elongation in the cytosol (FAS I system)
• Fatty acid elongation via elongase pathway of ER
• Glycosylphosphatidylinositol (GPI) anchor biosynthesis
• Inositol phosphate metabolism
• N-Glycan biosynthesis
• Phosphatidylcholine metabolism
• Phosphatidylethanolamine and phosphatidylserine metabolism
• Recycling of phospholipids
• Sphingomyelin and ceramide metabolism - In addition to salvage of sphingomyelin and its hydrolysis to ceramide de novo biosynthesis of ceramide is present.
• Terpenoid metabolism

Cryptosporidium parvum

• Fatty acid elongation in the cytosol (FAS I system)
• Fatty acid elongation via elongase pathway of ER
• Glycosylphosphatidylinositol (GPI) anchor biosynthesis
• Inositol phosphate metabolism
• N-Glycan biosynthesis
• Phosphatidylcholine metabolism
• Phosphatidylethanolamine and phosphatidylserine metabolism
• Recycling of phospholipids
• Sphingomyelin and ceramide metabolism - De novo biosynthesis of ceramide is absent.
• Terpenoid metabolism

Cryptosporidium hominis

• Fatty acid elongation in the cytosol (FAS I system)
• Fatty acid elongation via elongase pathway of ER
• Glycosylphosphatidylinositol (GPI) anchor biosynthesis
• Inositol phosphate metabolism
• N-Glycan biosynthesis
• Phosphatidylcholine metabolism
• Phosphatidylethanolamine and phosphatidylserine metabolism
• Recycling of phospholipids
• Sphingomyelin and ceramide metabolism - De novo biosynthesis of ceramide is absent.
• Terpenoid metabolism