| Shape |
Description |
|---|
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Any commodity metabolite in the reactions (main substrates and products and does not include the cofactors). It does not include protein, DNA and RNA metabolites |
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Simple molecules as aliased metabolites or compounds. They are also known as currency metabolites. These are co-substrates and co-products including cofactors. |
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Proteins including enzymes as commodity metabolites (main substrates and products) in reactions |
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Protein molecules as aliased metabolites or compounds. These are proteins which undergo modification in the reaction and act as co-substrates or co-products. |
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Cations (mainly H+, Ca2+) as aliased metabolites in reactions |
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tRNAs and aminoacyl-tRNAs |
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mRNAs as metabolites in reactions |
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Monofunctional enzymes (single EC number annotation) |
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Enzymes which should be present in the organism to provide complete metabolic pathway, but, gene is missing in the present gene models. |
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Multifunctional enzymes. The figure shows a bifunctional enzyme with two EC number annotations. The outer rectangle represents a single protein (gene) and the inner rectangles represent each function (single EC number). |
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Multimodule containing multifunctional enzyme. The figure shows a multifunctional enzyme (from single gene) with two modules. Each module might have more than 1 enzyme function (more than 1 EC numbers). There can be more than one module of same function as in the case of FASI. The only example of this category in these metabolic pathways is FASI (2.3.1.85). |
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Multiprotein complex/Multi-subunit protein - Each protein complex has more than one polypeptides (encoded by more than 1 genes) carrying out same or different functions. This is used in electron transport chain pathway for different mitochondrial complexes. |
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Non-enzymatic proteins (not even partial EC numbers). E.g. Acyl-CoA binding protein, transcription factors etc. |
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Proteins annotated to known transporter functions. |
